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Aprocitentan

Product Specifications

CAS Number

1103522-45-7

Synonyms

ACT-132577

Target

Endothelin Receptor

Applications

GPCR & G Protein

Molecular Formula

C16H14Br2N6O4S

Additionnal Information

Aprocitentan (ACT-132577) is a pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual antagonist of ETA/ETB with IC50 values of 3.4 nM and 987 nM, and pA2 values of 6.7 and 5.5, respectively.

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