BMS-986397
Product Specifications
CAS Number
2564486-44-6
Synonyms
CC-91633
Target
Casein Kinase
Applications
Cell Cycle
Molecular Formula
C21H16ClF3N4O4
Additionnal Information
BMS-986397 (CC-91633) is a potent and selective thalidomide-derived molecular glue degrader of CK1α and a modulator of CRBN E3 ubiquitin ligase. As a first-in-class CELMoD agent, it exhibits strong anti-leukemic activity in AML (Acute Myeloid Leukemia) and HR-MDS (High-Risk Myelodysplastic Syndrome) models, with enhanced efficacy and potency for hematologic malignancies and immunomodulation.
More Discoveries
Explore Other Products
Browse additional items from our catalog
KD3741502-100 100 Reactions
AMD Bacteroides fragilis (B. fragilis) PCR Detection Kit
Sign In for Pricing
View Details 
orb348328 500 μL
F (ab') 2 Rat IgG (H&L) Antibody Rhodamine Conjugated
Sign In for Pricing
View Details 
MBS6181472-01 0.1 mL
NDRG2 (NDRG Family Member 2, DKFZp781G1938, FLJ25522, KIAA1248, SYLD) (HRP)
Sign In for Pricing
View Details MBS6181472-02 5x 0.1 mL
NDRG2 (NDRG Family Member 2, DKFZp781G1938, FLJ25522, KIAA1248, SYLD) (HRP)
Sign In for Pricing
View Details MBS2080809-01 0.1 mL
FITC-Linked Polyclonal Antibody to FOS Like Antigen 1 (FOSL1)
Sign In for Pricing
View Details