MGD-28
Product Specifications
CAS Number
2991818-13-2
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C33H34FN7O3
Additionnal Information
MGD-28 is a potent and orally active degrader of Cereblon (CRBN) -dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM) . It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6233152-01 0.1 mL
GTF2A2 (Transcription Initiation Factor IIA Subunit 2, General Transcription Factor IIA Subunit 2, TFIIA p12 Subunit, TFIIA-12, TFIIAS, Transcription Initiation Factor IIA gamma Chain, TFIIA-gamma, TF2A2) (MaxLight 750)
Sign In for Pricing
View Details MBS6233152-02 5x 0.1 mL
GTF2A2 (Transcription Initiation Factor IIA Subunit 2, General Transcription Factor IIA Subunit 2, TFIIA p12 Subunit, TFIIA-12, TFIIAS, Transcription Initiation Factor IIA gamma Chain, TFIIA-gamma, TF2A2) (MaxLight 750)
Sign In for Pricing
View Details 
GTR15294932 1 Vial
Lentiviral mouse Fbxw8 shRNA (UAS) - Lentiviral mouse Fbxw8 shRNA (UAS) (25)
Sign In for Pricing
View Details MBS1403352-01 0.05 mg (E-Coli)
Recombinant Heliothis zea nuclear polyhedrosis virus Very late expression factor 1 (VLF-1)
Sign In for Pricing
View Details MBS1403352-02 0.05 mg (Yeast)
Recombinant Heliothis zea nuclear polyhedrosis virus Very late expression factor 1 (VLF-1)
Sign In for Pricing
View Details