MGD-28
Product Specifications
CAS Number
2991818-13-2
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C33H34FN7O3
Additionnal Information
MGD-28 is a potent and orally active degrader of Cereblon (CRBN) -dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM) . It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.
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