RGT-018
Product Specifications
CAS Number
2794934-49-7
Target
Ras
Applications
Apoptosis
Molecular Formula
C27H24F3N7O2
Additionnal Information
RGT-018, is a potent and selective inhibitor of SOS1. It blocks the interaction of KRAS:SOS1 with an IC50 of 8 nM and inhibited KRAS signaling and the proliferation of KRAS-driven cancer cells. It may exhibit potent anticancer activity against NSCLC, colorectal cancer, and pancreatic cancer.
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