OPB-171775
Product Specifications
CAS Number
2131210-15-4
Target
PDE
Applications
Metabolism
Molecular Formula
C15H18F2N2O3
Additionnal Information
OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) . This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST) .
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