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OPB-171775

Product Specifications

CAS Number

2131210-15-4

Target

PDE

Applications

Metabolism

Molecular Formula

C15H18F2N2O3

Additionnal Information

OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) . This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST) .

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