MTX-531
Product Specifications
CAS Number
2791417-66-6
Synonyms
NSC827271
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C22H20ClN5O2S
Additionnal Information
MTX-531 (NSC827271) is a first-in-class, potent and selective inhibitor of EGFR and PI3Kα with an IC50 of 14.7 nM and 6.4 nM, respectively. It may play a role in treating Head and Neck Squamous Cell Carcinoma (HSNCC), squamous lung cancers, and certain EGFR/PI3K-driven triple-negative breast cancers.
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