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KT-413

Product Specifications

CAS Number

2655656-99-6

Synonyms

IRAK degrader-1, zomiradomide

Target

IRAK

Applications

Immunology & Inflammation

Molecular Formula

C45H48F3N7O6S

Additionnal Information

KT-413 (IRAK degrader-1, zomiradomide) is a dual-function PROTAC molecule and a potent degrader of interleukin-1 receptor associated kinase 4 (IRAK4) and the transcription factors Ikaros and Aiolos by acting as both a heterobifunctional degrader and a molecular glue. It can be used in research for developing therapies targeting the activated B-cell (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) .

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