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Pico145

Product Specifications

CAS Number

1628287-16-0

Synonyms

HC-608

Target

TRP Channel

Applications

Neuronal Signaling

Molecular Formula

C23H20ClF3N4O5

Additionnal Information

Pico145 (HC-608) is a selective inhibitor of TRPC1/4/5 channels. It inhibits (−) -englerin A-activated TRPC4/TRPC5 channels, with IC50 values of 0.349 and 1.3 nM, respectively. It exhibits no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
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