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PK 11195

Product Specifications

CAS Number

85532-75-8

Synonyms

RP 52028

Target

Others

Applications

Others

Molecular Formula

C21H21ClN2O

Additionnal Information

PK 11195 (RP 52028) is a translocator protein (TSPO) ligand, a potent and selective antagonist of peripheral benzodiazepine receptorwith high affinity Ki of 3.1 nM in cerebellum and 4.1 nM in spinal cord. It is also an antagonist of human constitutive androstane receptor (hCAR), and human pregnane X receptor (PXR) . It displaces [3H] RO5-4864 from its binding sites across organs and also targets Leishmania in chemotherapy.

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