PK 11195
Product Specifications
CAS Number
85532-75-8
Synonyms
RP 52028
Target
Others
Applications
Others
Molecular Formula
C21H21ClN2O
Additionnal Information
PK 11195 (RP 52028) is a translocator protein (TSPO) ligand, a potent and selective antagonist of peripheral benzodiazepine receptorwith high affinity Ki of 3.1 nM in cerebellum and 4.1 nM in spinal cord. It is also an antagonist of human constitutive androstane receptor (hCAR), and human pregnane X receptor (PXR) . It displaces [3H] RO5-4864 from its binding sites across organs and also targets Leishmania in chemotherapy.
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