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Taminadenant

Product Specifications

CAS Number

1337962-47-6

Synonyms

NIR178, PBF509

Target

Adenosine Receptor

Applications

GPCR & G Protein

Molecular Formula

C10H8BrN7

Additionnal Information

Taminadenant (NIR178, PBF509) is a non-xanthine and non-furan antagonist of adenosine A2A receptor (A2AR) . It can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with Kb values of 72.8 nM and 8.2 nM, respectively. It exhibits potential utility for Parkinson’s disease (PD) treatment.

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