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BMS-986235

Product Specifications

CAS Number

2253947-47-4

Synonyms

LAR-1219

Target

FPR

Applications

GPCR & G Protein

Molecular Formula

C18H17F2N3O3

Additionnal Information

BMS-986235 (LAR-1219) is a selective, orally active and potent agonist of formyl peptide receptor 2 (FPR2), with EC50 values of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 therapy shows promising improvements in cardiac structure and function in a mouse model of heart failure, highlighting its potential for preventing the progression of heart failure.

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