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Amredobresib

Product Specifications

CAS Number

1610044-98-8

Synonyms

BI894999

Target

Epigenetic Reader Domain

Applications

Epigenetics

Molecular Formula

C26H29N9

Additionnal Information

Amredobresib (BI894999) is an oral inhibitor of BET, which acts as an acetyl-lysine mimic. It prevents the bromodomains BRD4-BD1 and BRD4-BD2 from binding to acetylated histones, with an IC50 of 5 nM for BRD4-BD1 and 41 nM for BRD4-BD2.

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