Amredobresib
Product Specifications
CAS Number
1610044-98-8
Synonyms
BI894999
Target
Epigenetic Reader Domain
Applications
Epigenetics
Molecular Formula
C26H29N9
Additionnal Information
Amredobresib (BI894999) is an oral inhibitor of BET, which acts as an acetyl-lysine mimic. It prevents the bromodomains BRD4-BD1 and BRD4-BD2 from binding to acetylated histones, with an IC50 of 5 nM for BRD4-BD1 and 41 nM for BRD4-BD2.
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