VLS-1488 (KIF18A-IN-6)
Product Specifications
CAS Number
2914879-10-8
Synonyms
KIF18A-IN-6
Target
Kinesin
Applications
Cytoskeletal Signaling
Molecular Formula
C28H37N3O5S2
Additionnal Information
VLS-1488 (KIF18A-IN-6) is an oral inhibitor of KIF18A with an IC50 of 0.016 μM. KIF18A is a mitotic kinesin motor protein that localizes at the plus-end of kinetochore microtubule spindle fibers and is crucial for cell division in aneuploid cancer cells with high chromosomal instability (CIN) .
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