MEN1703 (SEL24, SEL24-B489)
Product Specifications
CAS Number
1616359-00-2
Synonyms
SEL24, Pim/flt3 kinase inhibitor SEL24
Target
Pim
Applications
JAK/STAT
Molecular Formula
C15H18Br2N4O2
Additionnal Information
MEN1703 (SEL24-B489, SEL24, Pim/flt3 kinase inhibitor SEL24) is a potent, type I, orally active, dual inhibitor of PIM and FLT3-ITD, that exhibits Kd values of 2 nM for PIM1, 2 nM for PIM2 and 3 nM for PIM3, respectively. MEN1703 exhibits its broad therapeutic potential in treatment of acute myeloid leukemia.
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