Avitinib maleate
Product Specifications
CAS Number
1557268-88-8
Synonyms
Abivertinib maleate, AC0010 maleate, AC0010MA
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C26H26FN7O2.C4H4O4
Additionnal Information
Avitinib maleate (Abivertinib maleate, AC0010 maleate, AC0010MA) is a third-generation, irreversible, and orally active selective inhibitor of EGFR. It displays IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M, and wild-type EGFR. Avitinib maleate also acts as an inhibitor of BTK that induces apoptosis of BTK in mantle cell lymphoma.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040103-500 1x 500 µL
P55;50 EBV-Early Antigen (1108-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
I-2901-1 1 mg
Ferritin Conjugated Sophora japonica (Pagoda Tree) -SJA-
Sign In for Pricing
View Details 
TRC-D073605-250MG 250 mg
3,6-Dichlorobenzene-1,2,4-tricarboxylic acid
Sign In for Pricing
View Details 
LC432740 20 µg
SCP3 (SYCP3) (NM_001177949) Human Over-expression Lysate
Sign In for Pricing
View Details