ZINC69391
ZINC69391, a specific Rac1 inhibitor, interferes with Rac1-GEF interaction by masking Trp56 residue on Rac1 surface. ZINC69391 interferes with the interaction of Rac1 with Dock180 and reduces Rac1-GTP levels. ZINC69391 induces apoptosis, and shows antiproliferative and antimetastatic effects[1][2][3].
Product Specifications
CAS Number
303094-67-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Apoptosis; Ras
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc69391.html
Purity
99.76
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N=C(NC1=CC=CC=C1C(F)(F)F)NC2=NC(C)=CC(C)=N2
Molecular Formula
C14H14F3N5
Molecular Weight
309.29
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD81 / TAPA-1 (1.3.3.22), CF488A conjugate, 0.1mg/mL
TNF alpha (J2D10), CF640R conjugate, 0.1mg/mL
CD35 / CR1 (E11), CF640R conjugate, 0.1mg/mL
Napsin A (Lung Adenocarcinoma Marker) (NAPSA/1865R), CF594 conjugate, 0.1mg/mL
CD34 (HPCA1/763), CF405S conjugate, 0.1mg/mL
