Bisindolylmaleimide VIII (acetate)
Product Specifications
CAS Number
138516-31-1
Synonyms
Ro 31-7549 acetate
Target
PKC
Applications
Cytoskeletal Signaling
Smiles
C[N]1C=C (C2=CC=CC=C12) C3=C (C (=O) NC3=O) C4=C[N] (CCCN) C5=CC=CC=C45.CC (O) =O
Molecular Formula
C24H22N4O2.C2H4O2
Additionnal Information
Bisindolylmaleimide VIII (acetate) (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC, also exerting IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
Storage Conditions
3 years -20°C powder
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