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R1530

Product Specifications

CAS Number

882531-87-5

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

COC1=C (F) C=C2C (=C1) N=C3NNC (=C3N=C2C4=CC=CC=C4Cl) C

Molecular Formula

C18H14ClFN4O

Additionnal Information

R1530 is a highly potent, orally bioavailable, dual-acting mitosis/angiogenesis inhibitor for the treatment of solid tumors, which can inhibit vascular endothelial growth factor receptor 2 (VEGFR2) and fibroblast growth factor receptors 1 (FGFR1) with IC50s of 10 nM and 28 nM, respectively.

Storage Conditions

3 years -20°C powder

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