Doxorubicin
Product Specifications
CAS Number
23214-92-8
Synonyms
Adriamycin, Hydroxydaunorubicin, DOX
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
COC1=C2C (=O) C3=C (C (=C4CC (O) (CC (OC5CC (N) C (O) C (C) O5) C4=C3O) C (=O) CO) O) C (=O) C2=CC=C1
Molecular Formula
C27H29NO11
Additionnal Information
Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.
Storage Conditions
3 years -20°C (in the dark) powder1 year -80°C (in the dark) in solvent
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