STAT5-IN-2
Product Specifications
CAS Number
2111834-61-6
Target
STAT
Applications
Apoptosis
Smiles
CC1 (C) CCN (CCOC2=CC3=C ([NH]C=C3) C=C2) C4=C1C=C (C=C4) C5=CN=CC=C5
Molecular Formula
C26H27N3O
Additionnal Information
STAT5-IN-2 inhibits the growth of acute and chronic myeloid leukemia cells and the phosphorylation and transcriptional activity of STAT5, but not STAT3, AKT, or Erk1/2 phosphorylation, with minimal effects on bone marrow stromal cells that play vital functions in the microenvironment of hematopoietic and leukemic cells.
Storage Conditions
3 years -20°C powder
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