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STAT5-IN-2

Product Specifications

CAS Number

2111834-61-6

Target

STAT

Applications

Apoptosis

Smiles

CC1 (C) CCN (CCOC2=CC3=C ([NH]C=C3) C=C2) C4=C1C=C (C=C4) C5=CN=CC=C5

Molecular Formula

C26H27N3O

Additionnal Information

STAT5-IN-2 inhibits the growth of acute and chronic myeloid leukemia cells and the phosphorylation and transcriptional activity of STAT5, but not STAT3, AKT, or Erk1/2 phosphorylation, with minimal effects on bone marrow stromal cells that play vital functions in the microenvironment of hematopoietic and leukemic cells.

Storage Conditions

3 years -20°C powder

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