TGFβRI-IN-3
Product Specifications
CAS Number
2763602-67-9
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC1=CC=CC (=C1) C2=CC (=CC=N2) NC3=CC=NC4=C3C=CC (=C4) C5=CC=C (C=C5) [S; v6] (C) (=O) =O
Molecular Formula
C28H23N3O2S
Additionnal Information
TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology, inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4.
Storage Conditions
3 years -20°C powder
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