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KT-333

Product Specifications

CAS Number

2502186-79-8

Target

STAT

Applications

Apoptosis

Molecular Formula

C60H74ClN10O14PS

Additionnal Information

KT-333 is a first-in-class, potent, and selective heterobifunctional degrader of STAT3 that recruits the VHL E3 ligase for ubiquitin-proteasome-mediated degradation. It induces robust antitumor activity in preclinical models of ALK+ anaplastic large cell lymphoma (ALCL) .

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