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YD23

Product Specifications

CAS Number

2951015-29-3

Target

PROTAC

Applications

Others

Molecular Formula

C38H39FN8O7

Additionnal Information

YD23 is a PROTAC which induces the degradation of SMARCA2. It reduces chromatin accessibility in SMARCA4-deficient cells, affecting gene enhancers related to cell cycle and growth regulation, which leads to the downregulation of several cell cycle genes. It also selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.

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