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Irpagratinib

Product Specifications

CAS Number

2230974-62-4

Synonyms

ABSK011

Target

FGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C28H32F2N6O5

Additionnal Information

Irpagratinib (ABSK011) is a potent inhibitor of FGFR4 with an IC50 of < 10 nM in biochemical assays. It effectively suppresses FGFR4 auto-phosphorylation and disrupts downstream signal transduction. It also strongly inhibits tumor growth and induces regression in subcutaneous xenograft models.

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