What is the catalog number for R16?

The catalog number for R16 is E1973-25mg.

What sizes are available for R16?

R16 is available in the following size(s): 25 mg.

R16 is currently made to order / not held in immediate stock. Contact us for lead time.

What is the estimated delivery time for R16?

Estimated delivery time for R16 is approximately 15 business day(s), depending on your location.

R16

Product Specifications

CAS Number

6325-13-9

Synonyms

NSC29869, Nrf2-IN-3

Target

Nrf2

Applications

NF-κB

Molecular Formula

C22H26N4O4S

Additionnal Information

R16 (NSC29869, Nrf2-IN-3) is an inhibitor of NRF2 (nuclear factor erythroid 2-related factor 2) that selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions. It significantly enhances the sensitivity of KEAP1-mutated tumor cells to cisplatin and gefitinib.