What is the catalog number for AZD8421?

The catalog number for AZD8421 is E1972-100mg.

What sizes are available for AZD8421?

AZD8421 is available in the following size(s): 100 mg.

AZD8421 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AZD8421?

AZD8421 is manufactured by Bimake.

What is the estimated delivery time for AZD8421?

Estimated delivery time for AZD8421 is approximately 15 business day(s), depending on your location.

AZD8421

Product Specifications

CAS Number

3047321-53-6

Target

CDK

Applications

Cell Cycle

Molecular Formula

C18H32N8O3S

Additionnal Information

AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2), with an IC50 against CDK2 of 9nM with selectivity over CDK1, CDK4 and CDK6. It also exhibits an anti-proliferative effect, effectively inhibits Rb phosphorylation, and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models.