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BAL-0028

Product Specifications

CAS Number

2842012-69-3

Target

NLRP3

Applications

Immunology & Inflammation

Molecular Formula

C24H22FN3O2

Additionnal Information

BAL-0028 (Compound 3), which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds tightly to the NACHT domain of NLRP3, with KD values ranging from 104 to 123 nM. BAL-0028 also exhibits anti-inflammatory activity.

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