BMS-986365
Product Specifications
CAS Number
2446928-30-7
Synonyms
CC-94676
Target
Androgen Receptor
Applications
Endocrinology & Hormones
Molecular Formula
C41H45F3N8O5S
Additionnal Information
BMS-986365 (CC-94676) is a potent and selective, heterobifunctional ligand-directed degrader (LDD) and antagonist of androgen receptor (AR), that effectively targets both wildtype and mutant forms of the androgen receptor (AR) in the cytoplasm and nucleus. It rapidly degrades AR, suppresses AR signaling, and shows promising clinical activity in inhibiting tumor growth in patients with metastatic castration-resistant prostate cancer (mCRPC) .
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