What is the catalog number for NVL-655?

The catalog number for NVL-655 is E1961-25mg.

What sizes are available for NVL-655?

NVL-655 is available in the following size(s): 25 mg.

NVL-655 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NVL-655?

NVL-655 is manufactured by Bimake.

What is the estimated delivery time for NVL-655?

Estimated delivery time for NVL-655 is approximately 15 business day(s), depending on your location.

NVL-655

Product Specifications

CAS Number

2739866-40-9

Synonyms

ALK-IN-27

Target

ALK

Applications

Protein Tyrosine Kinase

Molecular Formula

C23H22ClFN6O

Additionnal Information

NVL-655 is a selective inhibitor of anaplastic lymphoma kinase (ALK), with potential antineoplastic activity in the Ba/F3 xenograft model. It also exhibits significant inhibitory activity against ROS1, LTK, PYK2, TRKB, and FAK, with an IC50 ≤10-fold ALK and demonstrates high potency against specific ALK mutations, with an IC50 of <0.73 nM, 7 nM, 3 nM, 3 nM for G1202R, G1202R/L1196M, G1202R/G1269A and G1202R/L1198F respectively.