What is the catalog number for PF-05251749 (CK1-IN-2)?

The catalog number for PF-05251749 (CK1-IN-2) is E1927-5mg.

What sizes are available for PF-05251749 (CK1-IN-2)?

PF-05251749 (CK1-IN-2) is available in the following size(s): 5 mg.

Is PF-05251749 (CK1-IN-2) in stock?

PF-05251749 (CK1-IN-2) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PF-05251749 (CK1-IN-2)?

PF-05251749 (CK1-IN-2) is manufactured by Bimake.

What is the estimated delivery time for PF-05251749 (CK1-IN-2)?

Estimated delivery time for PF-05251749 (CK1-IN-2) is approximately 15 business day(s), depending on your location.

PF-05251749 (CK1-IN-2)

Product Specifications

CAS Number

1383376-92-8

Synonyms

CK1-IN-2

Target

Casein Kinase

Applications

Cell Cycle

Molecular Formula

C17H12FN3O2

Additionnal Information

PF-05251749 (CK1-IN-2, Compound Nr.4) is a potent, selective, brain-penetrant inhibitor of Casein Kinase 1 (CK1) in a concentration-dependent manner, with IC50 values of 33.1 nM for CK1d and 51.6 nM for CK1e. It also functions as an inducer of CYP3A, with the potential to treat circadian rhythm disruptions in Alzheimer's and Parkinson's diseases.