TI17
Product Specifications
CAS Number
1005178-02-8
Target
THR
Applications
Endocrinology & Hormones
Molecular Formula
C23H22N2O3
Additionnal Information
TI17 is an inhibitor of thyroid hormone receptor-interacting protein Trip13. TI17 efficiently suppresses the proliferation of multiple myeloma (MM) cells and triggers cell cycle arrest and apoptosis. Trip13, an AAA-ATPase involved in double-strand break (DSB) repair, is targeted by TI17, leading to impaired function and heightened DNA damage.
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