NRL-1049
Product Specifications
CAS Number
1973494-16-4
Synonyms
BA 1049
Target
ROCK
Applications
Cytoskeletal Signaling
Molecular Formula
C16H21N3O2S
Additionnal Information
NRL-1049 (BA 1049) is a small molecule selective inhibitor of ROCK2 with an IC50 of 0.59 μM. It exhibits potent efficacy in preserving the blood-brain barrier (BBB) and suppresses seizures after brain injury, and inhibits hemorrhagic transformation after ischemic stroke in mice.
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