HRO761
Product Specifications
CAS Number
2869954-34-5
Target
Others
Applications
Others
Molecular Formula
C31H31ClF3N9O5
Additionnal Information
HRO761 is a potent, selective, allosteric inhibitor of Werner syndrome RecQ helicase (WRN) . It binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation, and demonstrates anti-proliferative effects specifically in microsatellite instability (MSI) cancer cells.
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