TNG-462
Product Specifications
CAS Number
2760483-96-1
Target
PRMT
Applications
Epigenetics
Molecular Formula
C28H36N6O2S
Additionnal Information
TNG-462 is an orally active, potent and selective inhibitor of methylthioadenosine (MTA) -cooperative PRMT5. It exhibits significant antitumor activity, including durable regressions and complete responses, against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation solid tumors.
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