Inixaciclib
Product Specifications
CAS Number
2370913-42-9
Synonyms
NUV-422
Target
CDK
Applications
Cell Cycle
Molecular Formula
C26H30F2N6O
Additionnal Information
Inixaciclib (NUV-422) is a potent inhibitor of CDK2, CDK4, and CDK6. It inhibits the growth of glioma cell lines in vitro and exhibits antitumor activity in GB xenograft models, PDX models of HR+ HER2- metastatic breast cancer resistant to CDK4/6 inhibitors and prostate cancer resistant to anti-androgens.
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