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Inixaciclib

Product Specifications

CAS Number

2370913-42-9

Synonyms

NUV-422

Target

CDK

Applications

Cell Cycle

Molecular Formula

C26H30F2N6O

Additionnal Information

Inixaciclib (NUV-422) is a potent inhibitor of CDK2, CDK4, and CDK6. It inhibits the growth of glioma cell lines in vitro and exhibits antitumor activity in GB xenograft models, PDX models of HR+ HER2- metastatic breast cancer resistant to CDK4/6 inhibitors and prostate cancer resistant to anti-androgens.

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