Fulzerasib
Product Specifications
CAS Number
2641747-54-6
Synonyms
IBI351, GFH925
Target
Ras
Applications
Apoptosis
Molecular Formula
C32H30ClFN6O4
Additionnal Information
Fulzerasib (IBI351, GFH925) is an irreversible small molecule inhibitor for KRAS G12C mutation blocking KRAS pathway signaling pERK with an IC50 of 37 nM. It demonstrates potent anti-tumor activity in multiple KRAS G12C-mutant tumor models including human pancreatic cancer, human lung adenocarcinoma, colorectal adenocarcinoma, and lung cancer models.
More Discoveries
Explore Other Products
Browse additional items from our catalog
36517061 1.0 µg DNA
PGP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
IRBAMLRICTORAP684120UL 120 µL
Rabbit Anti RICTOR Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (IHC,ELISA) 120ul
Sign In for Pricing
View Details 