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Ninerafaxstat trihydrochloride

Product Specifications

CAS Number

2311824-72-1

Synonyms

MB-1018972 trihydrochloride, IMB-101 trihydrochloride

Target

Mitochondrial Metabolism

Applications

Metabolism

Molecular Formula

C22H29N3O5.3ClH

Additionnal Information

Ninerafaxstat trihydrochloride (MB-1018972 trihydrochloride, IMB-101 trihydrochloride) acts as a competitive inhibitor of 3-ketoacyl-CoA thiolase (3-KAT) to partially suppress fatty acid oxidation. It is an orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat trihydrochloride regulates myocardial substrate utilization and improves cardiac efficiency. Ninerafaxstat trihydrochloride is also used in research of cardiovascular diseases.

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