N6F11
Product Specifications
CAS Number
851398-76-0
Target
Ferroptosis
Applications
Apoptosis
Molecular Formula
C13H8Cl2N2OS
Additionnal Information
N6F11 is an inducer of ferroptosis. N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4), resulting in proteasomal degradation.
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