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N6F11

Product Specifications

CAS Number

851398-76-0

Target

Ferroptosis

Applications

Apoptosis

Molecular Formula

C13H8Cl2N2OS

Additionnal Information

N6F11 is an inducer of ferroptosis. N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4), resulting in proteasomal degradation.
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