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TC-E5002 (KDM2/7-IN-1)

Product Specifications

CAS Number

1453071-47-0

Synonyms

KDM2/7-IN-1

Target

Histone Demethylase

Applications

Epigenetics

Molecular Formula

C15H27NO4

Additionnal Information

TC-E5002 (KDM2/7-IN-1) is a selective inhibitor of histone demethylase KDM2/7 subfamily with IC50s of 6.8, 0.2, and 1.2 μM for KDM2A, KDM7A, and KDM7B, respectively. It is selective for the KDM2/7 subfamily over KDM4A, KDM4C, KDM5A, and KDM6A/UTX with IC50s of >120, 83, 55, and 100 μM, respectively. It exhibits antiproliferative activity, indicating its potential as an anticancer agent.

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