What is the catalog number for PF-06952229?

The catalog number for PF-06952229 is E1785-1g.

What sizes are available for PF-06952229?

PF-06952229 is available in the following size(s): 1 g.

Is PF-06952229 in stock?

PF-06952229 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PF-06952229?

PF-06952229 is manufactured by Bimake.

What is the estimated delivery time for PF-06952229?

Estimated delivery time for PF-06952229 is approximately 15 business day(s), depending on your location.

PF-06952229

Product Specifications

CAS Number

1801333-55-0

Synonyms

UNII-1KKS7U3X86

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Molecular Formula

C23H24ClFN4O3

Additionnal Information

PF-06952229 (UNII-1KKS7U3X86) is a selective, orally available inhibitor of the serine/threonine kinase TGF-β receptor 1 (TGF-β-R1) . It inhibits pSMAD2 in both tumor and immune cells, reducing TGF-β signalling and reversing EMT in vitro. It modulates the tumor immune microenvironment and shows antitumor activity in mouse models.