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Merbarone

Product Specifications

CAS Number

97534-21-9

Synonyms

NSC 336628

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Molecular Formula

C11H9N3O3S

Additionnal Information

Merbarone (NSC 336628) is a catalytic inhibitor of topoisomerase II with IC50 of 120 μM, with anti-proliferative activity against human cancer cells. Merbarone acts primarily by blocking topoisomerase II-mediated DNA cleavage.

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