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Limertinib

Product Specifications

CAS Number

1934259-00-3

Synonyms

ASK120067

Target

EGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C29H32ClN7O2

Additionnal Information

Limertinib (ASK120067) is an irreversible third-generation inhibitor of EGFRT790M with IC50 of 0.3 nM, with selectivity over EGFRWT having IC50 of 6.0 nM. It exhibits potent anti-proliferation activity in non-small cell lung cancer (NSCLC) tumor cells.

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