PBIT
Product Specifications
CAS Number
2514-30-9
Target
Histone Demethylase
Applications
Epigenetics
Molecular Formula
C14H11NOS
Additionnal Information
PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. It inhibits JARID1B (KDM5B/PLU1), JARID1Aand JARID1C with an IC50 of 3 μM, 6 μM and 4.9 μM respectively. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.
More Discoveries
Explore Other Products
Browse additional items from our catalog